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Product Detail

JWH-200

$150.00$1,800.00

JWH 210 is a potent cannabimimetic alkylindole, binding the central cannabinoid and peripheral cannabinoid receptors with Ki values of 0.46 and 0.69 nM, respectively.1 The effects of JWH 210 in whole cells or organisms have not been evaluated.

Stimulant
Stimulants excite the nervous system and increase physiological function.

Description

DESCRIPTION

JWH-200 Buy Legal Online

JWH-200 is a potent cannabimimetic alkylindole, binding the central cannabinoid and peripheral cannabinoid receptors with Ki values of 0.46 and 0.69 nM, respectively.1 The effects of JWH-200 in whole cells or organisms have not been evaluated.

JWH-200 Stimulant

Stimulants excite the nervous system and increase physiological function.

Research Chemical
Research chemicals are drugs

Dose Oral

Light               50-100mg
Common   100-200mg
Strong              200mg+

Duration          Oral Hours

Onset              Oral Minutes
After Effect      2-4 hours

JWH 200 is an aminoalkylindole that acts as a cannabinoid (CB) receptor ligand. It binds to the CB1 receptor with high-affinity (IC50 = 7.8-42 nM).1,2 The effects of JWH 200 in locomotor activity, tail-flick latency, hypothermia, and ring-immobility tests are comparable or superior to Δ9THC or WIN 55,212.3 It potently inhibits the contraction of electrically-stimulated murine vas deferens (IC50 = 3.7-6.0 nM).4,5

In vitro and in vivo (both with and without enzymatic hydrolysis) samples were purified by solid-phase extraction and analyzed using liquid chromatography. Electrospray ionization high-resolution Orbitrap mass spectrometry was used for the identification of the metabolites. The metabolite formed by consecutive morpholine cleavage and oxidation of the remaining side chain to a carboxylic group was detected in the highest amounts with the longest detection time.

 

Additional information

Weight :

10g, 20g, 50g, 100g, 500g, 1kg

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